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10.3390/biom12030371 168 PengS.LiaoL.DengH.LiuX.LinQ.WuW

found that acetaminophen causes concentration-dependent neuronal death in vitro at concentrations that are reached in human plasma during acetaminophen overdose, and are reached in the cerebrospinal fluid of rats for 3 h following doses that are below those required to induce acute hepatic failure in rats