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The protective effects of low dose carbon monoxide in the -synuclein model are associated with increases in cathepsin D and reduced -synuclein pathology To determine the mechanism by which CO promoted survival of dopaminergic neurons, we next assessed whether CO administration affected cellular mechanisms of protein degradation, including autophagy and lysosomal function, as well as levels of Syn and Syn aggregates, which have been proposed to mediate neuropathology in PD patients 1

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The results are listed in Table 4

FTSE 100-listed BAT, which sells Lucky Strike and Camel cigarettes, makes around a quarter of its revenue from menthol brands after buying Newport as part of a 38bn acquisition of RJ Reynolds last year