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The mean stroke volume was 71.37 cm 3 (SD 90.1 cm 3 )

Tirzepatide (Mounjaro, Zepbound) is an FDA-approved dual GIP/GLP-1 receptor agonist for type 2 diabetes and chronic weight management, but not all patients experience expected results

Lancet 393 (10182), 17451759

Any changes would require either: Comprehensive clinical development demonstrating safety and efficacy Substantial changes in federal drug policy The scientific community continues to see value in the mechanismpreclinical research continuesbut commercial therapeutic development remains stalled

We also thank Joan Brugge and the Ludwig Cancer Center at Harvard Medical School for their support