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Endobronchial biopsies from habitual marijuana-only smokers reveal widespread histopathologic alterations that are recognized as precursors to the subsequent development of malignancy [52], such as squamous cell metaplasia and cellular atypia, comparable to those observed in biopsies from tobacco-only smokers [53]

Thus, the present study applied a recently developed GBC method that could identify specific nodes or hubs influenced by smoking

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