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Many also used subjects known to appeal to youth and young adults such as young models and themes of rebellion, socializing, or a night out which were present in 40% of ads across all products, including in 78% of ads promoting e-cigarettes and heated tobacco products

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EMT plays a critical role in the development of smoking-related COPD airway remodeling disease and related lung cancer, especially in smoking-related COPD, where it may lead to airway remodeling, obstruction/occlusion, and tumor development