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BP and HR changes were compared among (1) different study groups (users of high, low, and zero nicotine products) and (2) pooled continuous smoking phenotype classification (same phenotype from week 12 to -52), with participants classified as quitters (completely quit smoking), reducers (50 % reduction in smoking consumption) and failures ( 45 years old) have d higher systolic (but not diastolic) BP compared to non-smokers when adjusted for age, body mass index, social class, and alcohol intake [9]