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148 In an observational study that followed 222 subjects with a history of DVT for six years, those taking 200 mg pycnogenol per day had lower risks of recurrent DVT and post-thrombotic syndrome compared with those treated with blood thinner medications such as aspirin, ticlopidine (Ticlid), sulodexide (Aterina, a formulation composed of 80% low-molecular weight heparin), or no medication

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Real-world outcomes can differ because people often change their normal behaviour in a research environment, whereas real-world settings give us a stronger indication of how effective medications are in the more unpredictable environment of peoples day-to-day lives

ix Alonso-Fernandez P, et al