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People who plan to get frequent injections over long periods long-term safety is unknown

Furthermore, on day 42 of the study, cats in all L-carnitine supplemented groups showed a significantly lower respiratory quotient (RQ) compared to their baseline values and the control group throughout the restricted feeding period, indicating their bodies relied more heavily on fat for energy

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Journal of Thoracic Disease , 13 , 68976910

The metabolic adaptations that occur are limited to the enhanced expression of beta-3 adrenergic receptors in adipose tissue, which actually represents a favorable metabolic improvement rather than a dependence-creating change