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Use by males can cause reduced sperm count and abnormal sperm cells

We demonstrated that the pathological changes in the ME mucosa resulting from the induced acute bacterial OM were more severe and required a longer recovery period in the presence of comorbid CS exposure than in the absence of CS exposure

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[28] However, the quality of evidence, including both numbers of studies and patients as well as quality and risk of bias of those studies, was limited

Dangerous chemicals : E-cigarette liquid often contains harmful substances such as diacetyl , which can cause lung disease, volatile organic compounds (VOCs) , and heavy metals like lead