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The move has raised concerns around higher retail prices, potential demand slowdown, and margin pressure for cigarette manufacturers

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0.095% Delta-9 THC 584 MG THCa 58% THCa 97% Total Cannabinoids *This product is not avail

PMC 1635740

We think that while it is clear that different endpoints may yield quite different results, the human MOE for cannabis based on the endpoint psychotropic effects can be seen as general validation of the MOE concept, because the resulting values below 1 are expected as the psychotropic effect is the desired endpoint (and hence the psychotropic threshold dose is exceeded by drug users)