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Tirzepatide exhibits C-terminal homology to exenatide and is conjugated to a C20 fatty diacid moiety via a Lys-linked hydrophilic spacer, a modification strategy similar to that employed in semaglutide [20]

It is synthesised in the body from the amino acids lysine and methionine, primarily in the liver and kidneys, and is also obtained through dietary sources such as red meat, fish, and dairy products

Report any suspected side effects to the MHRA through the Yellow Card scheme (yellowcard

Its primary function is to increase insulin production while decreasing the glucose production in the liver

Understanding how semaglutide works and what to expect along the way helps set realistic goals