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Mounjaro is approved as a treatment for type 2 diabetes, while Zepbound is authorized as a treatment for obesity as well as sleep apnea

As a consequence, reaction in the solvent-free state requires substrate solubilization in the liquid enzyme, diffusion through the viscous melt, molecular access to the active site and conformational flexibility in the enzyme-polymer surfactant nanoconjugate

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doi: 10.1080/09513590.2022.2079629 28 TefaghGPayabMQorbaniMSharifiFSharifiYEbrahimnegad ShirvaniMSet al