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Zn-regulated transporter (ZRT), Fe-regulated transporter (IRT)-like protein ZIP family, ATP-binding cassette (ABC) transporters, the P-type metal ATPases, NRAMP family, multidrug resistance-associated proteins (MRP), CDF family of proteins, copper transporter (COPT) family proteins, pleiotropic drug resistance (PDR) transporters, YSL transporter, and CAX are among the well-characterized HM transporter proteins (Toyoda et al., 2008

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