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Suppositories provide very similar results to IV methods of administration since the ingredients in the suppository are absorbed by the wall of the rectum and carried straight into the systemic circulation (circumventing the entero-hepatic portal system where ingredients are broken down)

His extensive publication record includes over 200 papers examining neuroprotective and neuroregenerative therapies, with particular focus on multimodal treatment approaches

doi: 10.5414/cpp42073

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The choice should be based on the research objectives, condition under study, and desired outcomes