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It has been determined that the low solubility of a delivered drug, as well as the delivery of a drug in its neutral form, can increase the retention time at the target site, allowing for a longer duration of action (Patton and Byron 2007)

doi:10.1002/cbdv.200790152 Wieling W, France CR, van Dijk N, Kamel H, Thijs RD, Tomasulo P

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It depends if its just dissident-right think-tank stuff, he told me, or if anyone actually does anything. I dont know how that became a meme, he said about Thielbucks

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