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Studies show the consuming an excessive amount of vitamin B12 may: Increase the risk of cardiovascular events in people with diabetic nephropathy : A study published in JAMA sought to determine whether B vitamin therapy was able to slow the progression of diabetic nephropathy (kidney damage due to diabetes) and prevent vascular complications

Vitamin B12 is found almost exclusively in animal products, so if you eat a vegetarian or vegan diet, it can be tough to get enough

They also found that the Mcl-1 inhibitors were very selective and did not kill cells that rely on other members of the protein family