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Khaini is identified as a hazardous product as it has a damaging effect on the chromosomes and tumors suppressor genes resulting in oral cancers 3

If youre worried about managing stress without cigarettes, there are many healthy alternatives, from exercise to mindfulness techniques

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However, genome-wide association analysis did not identify any major-effect loci for tar content in this study, and even the top ten SNPs individually explained only 2.12-3.90% of the phenotypic variance, suggesting a predominantly polygenic architecture with dispersed small-to-moderate effects

So, to recap: Both synthetic and naturally-derived nicotine pouches are considered tobacco-free