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Hormonal Boost: Tirzepatide gives a boost to GLP-1 and GIP, which help regulate your appetite, how your body uses glucose, and how much insulin it produces. 2

Evidence-based guidelines recommend 1.2-1.5 grams of protein per kilogram of ideal body weight dailysubstantially higher than standard recommendationsto preserve lean muscle mass during treatment

Current data suggest that when chyme enters the duodenum it triggers GIP release in the proximal gut

For example, if you experience cramping and diarrhoea, having loperamide (Imodium) on hand to take occasionally can be a relief (though avoid overuse, especially if you swing to constipation)

NCT03861052), insulin glargine (ClinicalTrials.gov registration no