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Dosing began at 0.25 mg of each active drug and escalated every four weeks until the full 2.4 mg dose was reached by week 16

Read article First week on GLP-1: what to expect day by day Practical guide to your first week on semaglutide or tirzepatide what you'll feel, how to handle the first injection, warning signs, and day-by-day tips

However, comprehensive medical history and individualized risk-benefit assessment remain essential components of prescribing decisions