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Many harmful and potentially carcinogenic substances are present in mainstream smoke

Venous ulcer Diabetic foot ulcer Failing skin graft Smoking and infections Smoking is associated with a greater likelihood or severity of: Bacterial wound infections, most often caused by Staphylococccus aureus and Streptococcus pyogenes Candida albicans infection, particularly in the mouth Viral infections, especially human papillomavirus (HPV), including genital warts

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Tobacco use is a leading cause of multiple cancers such as lung, mouth, throat cancers, stomach, and colorectal cancers, as well as some types of leukaemia