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We think that while it is clear that different endpoints may yield quite different results, the human MOE for cannabis based on the endpoint psychotropic effects can be seen as general validation of the MOE concept, because the resulting values below 1 are expected as the psychotropic effect is the desired endpoint (and hence the psychotropic threshold dose is exceeded by drug users)

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Certain areas and workplaces previously exempt under the Clean Indoor Air Law must now be smoke-free

Some of the health impairments caused by tobacco use are: Nicotine can kill brain cells and stop new ones from forming in the hippocampus, a brain region involved in memory