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A study revealed that intravenous administration of celastrol-albumin nanoparticles enables targeted delivery to renal mesangial cells, significantly alleviating glomerulonephritis at a higher efficacy than that of free celastrol [51]

Therefore, it is essential to thoroughly characterize these molecular forms to ensure proper formulation and avoid undesirable structural formations

Increase in DPP-IV in the intestine, liver and kidney of the rat treated with high fat diet and streptozotocin