Glutathione also helps to control the production of cytokines, the immune systems signalling and communication network
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It can be helpful in the treatment of conditions like liver disease and cancer, where detoxification is a critical component of treatment
On the other hand, mutants deficient for these two GSTs were neither more susceptible to isothiocyanate nor less aggressive than the wild-type parental strain during infection of the host plant Brassica oleracea
GSH can modulate the activity of various redox-sensitive signaling pathways, including the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway, which regulates the expression of antioxidant and detoxification genes, and the mitogen-activated protein kinase (MAPK) pathway, which regulates cell proliferation, differentiation, and apoptosis