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Description

When nutrients are abundant (i.e., when youre eating regularly), mTOR reduces autophagy because the cells have plenty of fuel

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Furthermore, GLP-1, PYY, and CCK receptors are localized in the ENS terminals

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39 , 40 In both studies, the cytotoxicity of APR-246 was independent of the TP53 mutational status

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Consistently, MAX2 has been reported to be induced under various abiotic stress conditions 183 , and overexpression of CsMAX2 in transgenic lines resulted in reduced MDA accumulation under salt, drought, and ABA stress, highlighting its protective role in stress mitigation 75

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