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Significantly higher breast cancer risk was observed in active smokers with high intensity and duration of smoking, as well as with initiation of smoking in the teenage years

In addition, the authors would like to acknowledge financial support from Natural Science Foundation of China

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Vitamin E (Tocopherol): Provides antioxidant protection

Although CSR reports highlight sustainability initiatives by the TCs, actual environmental impacts of manufacturing and transport remain a low priority for TCs (Reynolds American International 2018), and a low priority to date for tobacco control advocates (Framework Convention Alliance and Campaign for Tobacco-Free Kids 2015)