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TDP-43 self-interaction is modulated by redox-active compounds Auranofin, Chelerythrine and Riluzole

Studies comparing localized versus systemic delivery for other biologics (botulinum toxin, platelet-rich plasma) suggest systemic routes produce more uniform results across larger treatment areas

Pentadecapeptide BPC 157 and the duodenal lesion

The dominant model is acute surgical transection or chemical injury in rats, evaluated over short-to-medium time courses