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Cotinine is the major metabolite of nicotine and further metabolised mainly to trans-3-hydroxy-cotinine, both quantifiable in body fluids and frequently applied biomarkers for recent tobacco exposure [4]

Hence, judging the direction and intensity and direction of the wind based on the smoke blown by a smoker could be construed as cheating

[18] This indicated that exposure to e-cigarette components in a susceptible time period of brain development could induce persistent behavioral changes

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Tobacco was the major model used to establish the principals and methods of plant somatic cell genetics including in vitro propagation of cells and tissues, totipotency of somatic cells, doubled haploid production and genetic transformation