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[14] As slaveholding increased, intense racial contrasts emerged and all-black labor units supervised by white planters came to replace mixed-race units

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190 (October 5, 2021): 55300439, US Food and Drug Administration, Premarket Tobacco Product Applications for Electronic Nicotine Delivery Systems (ENDS): Guidance for Industry , March 2023, US Food and Drug Administration, Preparing and Submitting a Premarket Tobacco Product Application, June 6, 2025, US Food and Drug Administration, Technical Project Lead (TPL) Review of PMTAs, See Altria Group, 9393 FTC (2021)