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There is no 5th or golden dose, and you should not try to get any remaining liquid out once you have finished your 4th dose

As-Sanie, S., Black, R., Giudice, L

Sustained weight loss in the 20 percent range over multiple years is clinically meaningful

It's not ideal because the IR is a moving target, but it's the best method I have found yet and certainly gets you in the ball park

Contact your GP if you experience severe abdominal pain (which may indicate pancreatitis), persistent vomiting or diarrhoea, symptoms of gallbladder problems, recurrent hypoglycaemia, sudden vision changes, or any signs of urinary tract infection such as burning when urinating or cloudy urine