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State Any product made from or derived from tobacco or nicotine, that is intended for human consumption, whether smoked, chewed, absorbed, dissolved, inhaled, snorted, sniffed or ingested by any other means, including cigars, cigarettes, chewing tobacco, pipe tobacco, snuff, e-cigarettes or electronic nicotine delivery systems as well as e-cigarettes and liquid nicotine containers (bottle or other container of any substance containing nicotine where the substance is sold, marketed or intended for use in an e-cigarette)

Not recommended for

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The final PMTA rule includes information on how to amend or withdraw an application, how FDA communicates with the applicant, and FDA's disclosure procedures