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A growing body of translational research suggests that IN delivery can achieve CNS therapeutic effects while minimizing systemic exposure, allowing patients to experience fewer adverse effects, such as anemia or gastrointestinal upset, which are common concerns with oral or intravenous chelators

Gene expression analysis of murine and human osteoarthritis synovium reveals elevation of transforming growth factor beta-responsive genes in osteoarthritis-related fibrosis

This is one of the unusual features that drives research interest

Dual action of the PN159/KLAL/MAP peptide: increase of drug penetration across Caco-2 intestinal barrier model by modulation of tight junctions and plasma membrane permeability