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Mean body weight at baseline for the 902 patients was 106.8 kg and mean BMI was 38.3 kg/m

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Measurement of growth parameters Primary root length and total seedling biomass were measured in order to evaluate the ITC-triggered growth inhibition of mutants compared to WT

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Unless otherwise specified, the following seeding densities per well/dish were used: 96-well plates: 5 10 3 cells (FLO-1, SKGT4 and OE33), 1.5 10 4 cells (OE19) and 1 10 4 cells (all others)

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