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Furthermore, GLP-1 receptor mRNA and protein have been reported in the brains of adult rodents and macaques [17]

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8.7 Hepatic Impairment Use of metformin in patients with hepatic impairment has been associated with some cases of lactic acidosis

Potential side effects associated with Zepbound include: Nausea and vomiting Abdominal pain Mild fatigue and headache Injection site reactions (rash, itching, swelling) Potential concerns associated with tirzepatide include: Interactions with birth control: Tirzepatide may decrease the effectiveness of oral hormonal birth control

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