[4] [6] This relationship is bidirectional and complex, involving: Inflammatory pathways that affect both metabolic and mental health Hormonal dysregulation impacting mood and stress responses Psychosocial factors including stigma, body image concerns, and chronic disease burden Lifestyle factors such as reduced physical activity and poor sleep quality When GLP-1 medications improve glycaemic control, facilitate weight loss, and enhance overall metabolic health, patients may experience secondary improvements in psychological wellbeing
Glutathione is involved in normal cellular antioxidant processes, and use during certain medical treatments should be evaluated by a qualified professional
It works fast and is safe enough to be used post-surgery or during pregnancy
Importantly, genetic or pharmacologic inhibition of MCP-1 or CCR2 improved NASH and IR in different mouse models of NAFLD [HFD, carbon tetrachloride (CCl4), MCD-diet, high-fat, high-sucrose diet] [138,139,140], with more prominent improvement shown in CCR2 versus MCP-1 blockade, probably because CCR2 is also a receptor for other chemokines, i.e., CCL7, CCL8, and CCL13 [129]
improved neurobehavioral outcomes
