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Black's interest in the topic began in 1946, when he spent a year working as a teaching and research assistant to Robert Cambpell Garry who was professor of physiology at St Andrew's University while his first wife, a fellow student studying biochemistry and physiology, completed her degree

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As a result, blood clotting proteins, immune cells, fat, and cholesterol accumulate at the site of damage, forming what is known as plaque

doi: 10.1186/s12967-024-05026-9 183 YuF.WangX.RenH.ChangJ.GuoJ.HeZ.et al