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Vitamin B 12 deficiency symptoms may include: strange sensations, numbness, or tingling in the hands, legs, or feet difficulty walking (staggering, balance problems) anemia a swollen, inflamed tongue difficulty thinking and reasoning (cognitive difficulties), or memory loss weakness fatigue While an experienced physician may notice the symptoms and be able to detect a vitamin B 12 deficiency with a good interview and physical exam, a blood test is needed to confirm the condition

These three hormone pathways play a key role in glucose metabolism and appetite regulation

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It also reduced the risk of cardiovascular death by 13% ( p =0.016), non-fatal stroke by 16% ( p =0.007), hospitalization for heart failure by 10% ( p =0.023), and all-cause mortality by 12% ( p =0.012) (6)

This review highlighted that oral tablets offer similar or better efficacy and tolerability compared to most injectable GLP-1s