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You might feel less hungry sooner than you see the scale move

"From the 4 mg dose, reaching nearly 20% weight loss with one escalation step, to the 12 mg dose that delivered a level of weight loss long associated with bariatric surgery, retatrutide offers the potential for a patient-centric approach to obesity

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It reduces angiotensin levels by targeting the synthesis of angiotensinogen (AGT), the most upstream component of the renin angiotensin aldosterone system (RAAS), a classic pathway for blood pressure regulation