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doi: 10.1007/s40263-013-0076-8

Published research has looked at chromium picolinate's relationship to insulin sensitivity and its use in the context of managing metabolic health, including a 2004 review in The Diabetes Educator on chromium's role in insulin resistance (PMID 15208835), a 2024 systematic review in Environmental Geochemistry and Health on chromium supplementation and type 2 diabetes (PMID 39541030), and toxicology literature in The Annals of Pharmacotherapy addressing chromium picolinate safety (PMID 9562138)

Additionally, be sure you are not taking too much glutathione, as it can lead to an upset stomach or diarrhea

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Symptoms of low levels of Vitamin B12 in your body include anemia, weakness, fatigue, heart palpitations, pale skin, constipation, diarrhea, bloating, loos of appetite, nerve problems such as tingling or numbness, muscle weakness, loss of vision, mental problems such as changes in mood and depression