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According to the NCBI LiverTox database, nicotine itself "has not been associated with liver test abnormalities or with clinically apparent hepatotoxicity." However, some recent studies have identified potential links between nicotine use and non-alcoholic fatty liver disease (NAFLD)

Of the patients two were female and five male, which corresponds to a female to male ratio of 2:5

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Characteristics of a Multistate Outbreak of Lung Injury Associated with E-Cigarette Use, or VapingUnited States, 2019