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Highlights: Smoking is a major contributor to male infertility, affecting sperm volume and motility The study reveals heightened stress response in the sperm cells of smokers Lifestyle choices significantly impact semen quality, with smoking having the most profound effect 8-12% of couples who want to have kids have trouble

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[63] [39] A human fetus appears to be at triple risk from maternal alcohol consumption: [64] [65] The placenta allows free entry of ethanol and toxic metabolites like acetaldehyde into the fetal compartment