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The antioxidant xCT/GPX4 signaling pathway has been demonstrated to be implicated in ferroptosis, where xCT protects cells from oxidative stress by importing cystine and reducing it to cysteine for GSH synthesis 24

FDA approves Ozempic for cardiovascular risk reduction in adults with type 2 diabetes and known heart disease, updates Rybelsus label [Internet] NovoNordisk-us.com 2020

With appropriate patient selection, monitoring, and medical supervision, weight loss injections can be used safely in most individuals, including many with cardiovascular risk factors or established heart disease

As these cases unfold, they serve as a poignant reminder of the need for vigilance in pharmaceutical oversight and the importance of informed consent in medical treatment

Who should not use GLP-1 medications: individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)