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Interplay of cytokines in the pathophysiology of atopic dermatitis: insights from murin models and human

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4.2 Neural pathway The vagus nerve is an essential component of the GBA, responsible for conveying metabolic signals from the gut microbiota to the CNS and regulating brain function

This protection is likely due to increased growth of new neurons in the hippocampus, improved signaling of brain-derived neurotrophic factor (BDNF), better synaptic function, and reduced brain inflammation (Nichol et al., 2008)