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showed the possible role of nuclear GSTpi in the acquisition of resistance to anticancer drugs by cancer cells (66, 67), it is unclear how GSTP translocated from the cytoplasm to nucleus and if in the macrophage, cytosolic GSTP could also enter into the nucleus

found that 7-isopentenoxycoumarin significantly induced melanogenesis at a dose of 40 m, with the highest induction of melanin at 72 h, and excitingly the induction was 6-fold greater than that of the control group, and the mechanism of action was to increase melanogenesis by elevating MITF and its downstream genes tyrosinases, TRP-1 and Trp-2

Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene

Lacy BE, Brenner DM, Chey WD