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Interestingly, within the UC group, current smoking presented a paradoxical protective effect, with an HR of 0.7569 (95% CI: 0.67880.844, p = 5.36e-7) compared to never-smoking individuals (Supplementary Table 1)

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Collins L, Glasser AM, Abudayyeh H, Pearson JL, Villanti AC

Involvement of oxidative stress The increase in reactive oxygen species (ROS) caused by smoking is thought to play a critical role in vascular endothelial dysfunction

Smokers dont feel deprived or like theyre smoking less substancetheyre experiencing intelligent formulation that removes unnecessary intensity while preserving what makes the brand distinctive