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Ramlau-Hansen CH, Toft G, Jensen MS, Strandberg-Larsen K, Hansen ML, Olsen J

While concerns over the negative health impacts of obesity remain, they are now in competition with concerns about the high cost and proper use of GLP1agonist medications, particularly at a time when other cost pressures may be growing. When such coverage is offered, is it common to impose conditions to qualify for it

Some promising approaches include the following: - Garlic-derived allicin: reduces TMAO in murine models (C57BL/6 mice), suggesting anti-atherosclerotic potential ( - TMA lyase inhibitors: synthetic compounds (e.g., fluoromethylcholine, FMC) that irreversibly inhibit CutC/D ( - Probiotics: specific strains can lower TMAO levels ( 1.5 Experimental approach Here, we report the results of an alternative approach based on the use of postbioticspreparations of inanimate microorganisms and/or their components, which confer health benefits to the hostas inhibitors of intestinal TMA lyase ( Lactobacillus paracasei LMG-S-26420 ferment for 72 h under anaerobic conditions in the presence of a freeze-dried botanical hydroalcoholic extract of garlic ( Allium sativum )