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Approved Indications: Type 2 Diabetes Mellitus (T2DM): As an adjunct to diet and exercise to improve glycemic control Cardiovascular Risk Reduction: Reduction in major adverse cardiovascular events (MACE)including CV death, non-fatal myocardial infarction, and non-fatal strokein adults with T2DM at elevated cardiovascular risk Mechanism of Action: A GLP-1 receptor agonist, semaglutide enhances glucose-dependent insulin secretion, suppresses glucagon release, and delays gastric emptyingresulting in improved glycemic control and favorable metabolic effects

The regulatory potential of top 20 ligand-receptor pairs (showed top 13) was represented in a dot plot

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Zheng W., Zhang Q.E., Cai D.B., Yang X.H., Qiu Y., Ungvari G., Ng C., Berk M., Ning Y.P., Xiang Y.T

It requires a valid prescription from a registered Australian medical practitioner

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