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The pharmacokinetic profile of orally administered ALCAR is complex and likely to be highly affected by endogenous concentrations

I see that @Steve_Combi has used higher doses before seeing a difference

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CoQ10 may interact with warfarin and antihypertensive medications

Fatigue is common and can be caused by many things, including: Iron deficiency Low vitamin D Thyroid issues Poor sleep quality or sleep apnoea Stress and burnout Low mood/anxiety Dietary patterns and hydration Long-term conditions Thats why we always recommend basing B12 treatment on clinical context, and ideally blood test results, rather than guessing