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Protein needs should be individualized, with general targets of 1.2-1.6 g/kg body weight for many adults, though lower amounts may be appropriate for those with chronic kidney disease or other conditions requiring protein modification

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Clinical trials used the same dosing for both men and women

The review is timely, as a number of primary reports shed exciting new insights into the role of the hypothalamus in regulating novel aspects of metabolic homeostasis including fatty liver disease. Abels next paper, Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression , homes in on this mechanism