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PLA1 cleaves the acyl ester bond at the sn-1 position to produce free fatty acids and lysophospholipids, whereas PLA2 cleaves at the sn-2 position to produce arachidonic acid and lysophosphatidic acid (Scandella and Kornberg, 1971

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Distinct effects of semaglutide and tirzepatide on metabolic and inflammatory gene expression in brown adipose tissue of mice fed a high-fat, high-fructose diet

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Central to this approach are degrons, short amino acid motifs, typically 610 residues in length, that mark proteins for recognition by E3 ubiquitin ligases