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Whole cigarettes (3 cigarettes from 3 different packages of the same variety) were extracted and analyzed in triplicate for the major commercial sensory cooling agents (menthol, WS-3, WS-23, WS-12, Frescolat MGA, Frescolat ML, Frescolat X-cool) by gas chromatography - mass spectrometry following published protocols (Supplementary file) 3

Though tobacco use is slowly declining and companies have been creating alternate products, those new items are a tiny portion of their sales

By the second half of the nineteenth century it was a city bursting with opportunities, ideas and wealth

However, its always important to consider health concerns and consult professionals for personalized advice

HINXTON, England, Nov